A team of researchers from the Ohio State College of Engineering and the Ohio State University Wexner Medical Center have been working on a novel technology based on a concept called tissue nanotransfection. Using this technology, the team can generate cells regardless of cell type within a patient’s body, in order to repair damaged parts and organs. Possible uses of this technology could be in the restoration of aging tissues, nerve cells, blood vessels, and even entire organs. The study was recently published in Nature Nanotechnology.
The Skin as Fertile Land
Dr. Chandran Sen, the director of Ohio State’s Center for Regenerative Medicine and Cell Based Therapies, compared the human skin to fertile land, where their regenerative technology can help grow the elements necessary for the development of any internal organ that is failing. The nanochip technology can be used to completely replace compromised or damaged organs. A majority of the tests were conducted on pigs and mice. The study involved evaluating the technology to reprogram skin cells to transform into vascular cells that could replace the ones within a badly injured leg where blood flow had gone awry. The leg was healed within two weeks and the active blood vessels started pumping blood in merely a week.
Unimaginable but Achievable
Sen also mentions that the reality of this treatment might be difficult to imagine, but is actually an achievable feat and has worked successfully nearly 98% of the attempts. The process could essentially be entirely noninvasive and not need more than a few seconds to be performed. The nanochip will not stay in the body once the cellular reprogramming is initiated. Additionally, the technology can monitor the body while its healing, ensuring immunity surveillance for the cells.